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2e) 20,21 or as a 2D cell line model also recapitulated findings from human CRC lines (Extended Data Fig

doi: 10.1038/nrmicro.2017.26 17 ArtsISGennarisAColletJ-F

The selected compounds for this assay were incubated at different concentrations (6 mg/mL, 3.0 mg/mL, 1.5 mg/mL, and 0.75 mg/mL of the samples, and 0.06 mg/mL, 0.03 mg/mL, 0.015 mg/mL and 0.0075 mg/mL of Alendronate) and incubated with 50 L of human erythrocytes resuspended in 950 L of saline solution

Key Takeaways High dose Vitamin C IV therapy can deliver significantly more vitamin C into your bloodstream compared to oral intake

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However, prolonged exposure to CS has been shown to have no effects on inflammatory mediators such as VCAM-1, ICAM-1 and cytokines in vivo [36, 37]