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GIP medications work by reducing hunger, and people then prefer to eat less throughout the day

This approach works well for diffuse back pain, multiple injury sites, or when local injection is impractical

By 104 weeks, approximately 77% of SELECT patients on dose were receiving the target semaglutide 2.4 mg weekly dose, which is lower than the corresponding proportion of patients in STEP 1 (89.6% were receiving the target dose at week 68) 14,21

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More common during rapid dose escalation