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Results were published in the The New England Journal of Medicine in May 2025

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Seek immediate medical attention (call 999 or attend A&E) if you develop: Severe, unrelenting abdominal pain Persistent vomiting with inability to keep down fluids Signs of severe dehydration (confusion, rapid heartbeat, very dark urine, no urination for 8+ hours) Symptoms of allergic reaction (difficulty breathing, facial swelling, severe rash) It is important to note that pancreatitis , though uncommon, is a recognised risk with GLP-1 receptor agonists

In addition, by monitoring renal indices such as estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio, pharmacists can detect early changes in kidney function and collaborate with physicians to adapt therapy

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