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At 4.8 mg total per weekly maintenance dose, each vial covers 4 full maintenance draws with a small residual

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94 Although the mechanistic basis remains less well defined than in the kidney, these findings suggest that highly organized tissue architecture may impose directional constraints on ferroptotic spread, effectively channeling the trajectory of injury through anatomical structure

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This is why a peptide-only approach without addressing these foundational factors often produces underwhelming results