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Moreover, in addition to alleviating hyperglycemia and hyperlipidemia, sitagliptin also ameliorated inflammation and oxidative stress by down-regulating JAK/STAT signaling pathway in diabetic rats, conferring evidence for the therapy of diabetic cardiomyopathy [106]
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Animal studies indicate dose-dependent effects, with toxic doses possibly affecting copper metabolism or interacting with embryonic development in hypersensitive models, warranting caution during pregnancy
Gabery S, Salinas CG, Paulsen SJ, et al
All bacteria were incubated at 37C unless otherwise requested
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