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For a broader overview of how these medications work, our GLP-1 overview is a useful companion
The precise mechanism of kidney-protective effects of GLP-1 RAs still remains elusive, but likely include direct kidney actions such as inducing natriuresis through NHE3 inhibition in the proximal tubules, suppressing the intrarenal renin-angiotensin system, ameliorating kidney ischemia/hypoxia [63, 64]
GLP-1 treatment should be considered within this broader risk-reduction strategy
It is recommended to store it in opaque containers and avoid direct sunlight
Mawer, R (6 de noviembre de 2018)
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