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The selectivity of FOXO4-DRI appears to be a major advantage: FOXO4-DRI peptide is particularly compelling due to its ability to disrupt the FOXO4-p53 interaction , a critical regulator of cellular senescence

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10.1080/09603123.2023.2210109 159 NarkwicheanA.MaaloufW.BaumgartenM.PolanskiL.Raine-FenningN.CampbellB.et al (2017)

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An outcome survey of 43 patients with Budd-Chiari syndrome due to Behets syndrome followed up at a single, dedicated center