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Most GH secretagogue peptides are stable in a mildly acidic environment
Exosomes derived from CAFs in PDAC do not exhibit gemcitabine resistance, however, CAFs promote chemotherapy resistance in PDAC cells by secreting exosomes and maintaining signal exchange with PDAC cells after gemcitabine treatment
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This therapy should not be used during pregnancy or breastfeeding
Since metformin is already contraindicated at eGFR 60), the copper load from therapeutic GHK-Cu doses is unlikely to cause accumulation
A., Thal, L
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