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Published data on isoform-specific NOS involvement remain variable and should not be generalized across all cell types or all preclinical models

Abizaid and Horvath, 2008)

What the patient actually receives depends on storage and handling after that

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Nausea ranged from approximately 11% at the lowest 1 mg dose to 64% in some intermediate-dose arms, with about 33% reported in the 9 mg fixed-dose arm (the highest-efficacy arm)

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