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The response in the nose is allergic rhinitis (swelling, fluid, sneezing), while activation in the lungs causes allergic asthma, fluid and mucus deep in the lungs, bronchial constriction, and coughing

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In humans, hemokinin 1 (HK-1), together with endokinins (EK) A, B, C and D, which originate from the different splice variants of the TAC4 gene (preprotachykinin C), have been found [102]