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Figure 2 4 Sources of probiotics: from traditional fermented foods to modern functional products The growing global focus on health and wellness is driving demand for functional foods, products designed to provide targeted benefits, such as enhanced disease resistance and prevention, that extend beyond basic nutritional value (98)

Sulfonylurea drugs interfere with the metabolism of alcohol, leading to acetaldehyde-related flushing when these patients imbibe alcohol

In contrast, the dose used in our study (10 g/kg/day) likely results in supraphysiological concentrations during the treatment period, which may be necessary to achieve therapeutic effects in a disease state where endogenous irisin production or signaling could be impaired

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10.1096/fj.201700115R FASEB J

Correct probe localization was verified by fluorescence microscopy (Supplementary figure 1)