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After accounting for total weight loss, researchers identified three factors linked to greater muscle loss on semaglutide: being older, being female, and eating less protein

These side effects may include nausea, vomiting, diarrhea, constipation, or abdominal pain

One landmark study showed participants lost an average of 15% of body weight over 68 weeks, with many experiencing changes within 4-8 weeks of consistent dosing

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