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GLP-1 side effects: what to expect and how to manage

If youre also losing water weight in the early weeks of treatment, as is common, electrolyte losses are compounded further

The review revisited SUSTAIN-6, where semaglutide-treated patients showed a hazard ratio of 1.76 for retinopathy complications compared with placebo. The discussion has since shifted toward whether rapid metabolic changerather than direct retinal toxicitymay explain the signal

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As a result, clinicians are shifting toward integrative strategies that prioritize the root cause over symptomatic quick fixes