For those using EAA supplementation, taking a dose around training (before or during exercise) may enhance the anabolic interaction between EAAs and exercise research suggests EAA taken prior to exercise produces a greater anabolic effect than post-exercise consumption, due to the amplified delivery of amino acids to muscle during exercise-induced increases in blood flow., When appetite suppression makes meals smaller or less frequent, EAA supplementation between meals helps maintain the total daily EAA availability needed for muscle maintenance
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In the case of tirzepatide, a recent meta-analysis of the SURPASS clinical trial programme did not identify any increased risk of EWDR (Popovic et al, 2024)
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Nearly half did so without consulting their doctor