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Anti-inflammatory peptides act on several pathways: modulating pro-inflammatory cytokines, inhibiting the NF-kB signaling pathway, shifting macrophages toward a healing state, and enhancing antioxidant defenses

Direct activation of cAMPPKA signaling, site-specific HSL phosphorylation, perilipin remodeling, ATGL regulation, mitochondrial enzyme activation, UCP1-dependent thermogenesis, and a comprehensive gene-expression program remain unproven unless directly measured in an AOD9604-specific experiment

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