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Once activated, these caspases cleave gasdermins to liberate the pore-forming N-terminal domains, enabling their targeting of cellular membranes to form large transmembrane pores, which disrupts cellular electrochemical gradient, and leads to water influx and cell swelling (160, 161)
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PubMed laboratory research record [PMID: 11595454] PubMed record related to this compound for laboratory literature review
Hashim, Z
Do not use for cellulite
While all studies adequately ascertained exposure and ensured comparability between outcome groups by controlling for confounders, 42% (n = 5) did not provide adequate sample representativeness and size, and 17% (n = 2) did not report the non-response rate
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