Both are designed for small, defined pockets of fat in people who are already close to their target weight
Side effects and risks : Though GLP-1 agents are generally well tolerated, they carry risk of gastrointestinal effects, possible rare pancreatitis, effects on gallbladder, etc
Last reviewed: May 25, 2026 Last updated: May 25, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
According to the researchers, up to 85.1% of those treated with survodutide achieved at least a 5% reduction in their weight, contrasting with only 38.8% in the placebo group who reached this goal
But the real driver is off-label weight loss use
Correlation analysis was performed with corAR1, which describes the within group correlation structure as an autoregressive process of order 1, and accounts for correlation between adjoining observations