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The decrease of glutathione levels has been detected in several AD mouse models including triple-transgenic (3X-AD-Tg) and APP/PS1 mouse 61,62
A few examples of the activities played by GSTs on antineoplastic agents and their contribution to drug resistance in cancer are the following: Cisplatin Platinum chemotherapeutic drugs are among the most extensively used anticancer agents 73
Kayamori K, Nagai Y, Zhong C, Kaito S, Shinoda D, Koide S, et al
& Filipowicz, W
10.1016/S0196-0644(95)70042-0 25
For detection on Western blot, a PhoA-specific first antibody (Sigma-Aldrich, #MAB1012 1:5000) and a goat-anti-mouse IRDye 800CW conjugate (LeiCor, Lincoln, NE, USA, #926-32210) were used (1:5000) according to the suppliers protocol
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