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Weight average (540 47 Kg), estimated by standardized measuring tape around the thorax, and was similar in all groups

After one year, people in the GLP-1 group could walk 13% farther, had more pain-free walking, had lower blood sugar, and lost more weight than people in the placebo group

Relative contraindications and special populations requiring careful consideration: Patients with severe hepatic impairment (Child-Pugh class C) should generally avoid these medications due to insufficient safety data

Ongoing: your physician adjusts your dose as your body adapts

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