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In mice, the dual agonist tirzepatide suppressed total caloric intake, while promoting intake of chow over high fat/sucrose diet (HFD)

Specifically, analyzed were the affected brain areas (04), cerebral (NTP-7, Level 3), cerebellar cortex (NTP-7, Level 6), and hippocampus, thalamus, and hypothalamus (NTP-7, Level 3) as follows (score 0 indicates no histopathologic change): score 1: small, patchy, complete, or incomplete infarcts (10% of the area affected)