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However, the saturation effect beyond this level implies that supplementation should be individualized, as excess B12 is unlikely to confer additional benefits
The corollary to this is that if, the brain is loaded with "dud" B12 in utero, or if the brain is exposed to vitamin B12 modifying agents such as Nitrous Oxide, it will be almost impossible to displace the altered vitamin B12.Forthis reason continuous release/delivery of vitamin B12 is essential
In two Phase 2 clinical trials covering stasis and pressure ulcers, TB4 accelerated complete wound closure by almost a month in patients who achieved full healing representing one of the most substantial healing acceleration outcomes observed for a peptide compound in a controlled clinical investigation
However, B 12 deficiency after gastric surgery does not usually become a clinical issue
London: National Institute for Health and Care Excellence (NICE)
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