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As cells become more responsive to insulin, the pancreas does not need to produce as much to maintain glucose control

Additionally, lymphocyte recruitment is mediated by distinct chemokine axes, including the CXCR6CXCL16 pathway for natural killer T (NKT) cells, the CXCR3CXCL9CXCL10 pathway for inflammatory hepatic CXCR3 + Th17 (ihTh17) cells, and the CCR2CCR5 signaling pathway for T cells [74, 144, 146, 147]

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