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Providers may evaluate markers such as P1NP (procollagen type I N-terminal propeptide) to guide initial titration

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These additional causes include sporadic genetic disorders, such as spinocerebellar atrophy type 27B, caused by GAA expansion in the FGF14 gene, and cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS), caused by biallelic expansions in the RFC1 gene

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doi:10.1016/j.jgr.2020.11.002 Irfan M, Jeong D, Saba E, et al

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