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However, the increased binding of NMDA receptors leads to increased post synaptic Ca + uptake and resultant excitotoxic loss of synapses and neurons via apoptotic mechanisms (Figure 2B

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Some common medication interactions to be careful of include: Utilizing Rybelsus in conjunction with insulin or insulin secretagogues (such as sulfonylureas) may elevate the likelihood of hypoglycemia, or low blood sugar