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While topical application has minimal systemic absorption, the precautionary principle suggests avoiding use during pregnancy unless a healthcare provider approves

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Curcumin Curcumin, chemically identified as 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, is the principal bioactive component derived from the rhizome of Curcuma longa L

PMID 40789979

Dysbiosis and intestinal permeability may increase endotoxin, inflammatory signaling and microbial metabolites delivered to the liver