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GLP-1R activation in the hypothalamus and brainstem suppresses appetite via POMC neuron stimulation and NPY/AgRP inhibition, slows gastric emptying, and potentiates glucose-dependent insulin secretion

Then there's the issue of contamination

Mitochondrial ferrous iron can mediate the synthesis of heme and iron-sulfur (Fe-S)

Saxenda is taken via injection and comes in a handy injection pen that patients can use at home, removing the need for healthcare workers to assist with the regular injections

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