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Immune checkpoint inhibitors (ICIs) are important novel drugs in cases with different types of cancers including malignant melanoma, non-small cell lung cancer, renal cell cancer, urothelial cancers, Hodgkin lymphoma, hepatocellular cancer, head and neck cancer, Merkel cell cancer and also mismatch repair-deficient solid tumors

Helps protect cells from oxidative stress

Improves peripheral circulation

Its naturally produced in the liver and is essential for eliminating heavy metals and other toxins from the body

Populations at a higher risk of vitamin B12 deficiency include people who are vegetarian or vegan, exclusively breastfed infants of vegan women, older adults, those with gastrointestinal disorders or who have had gastrointestinal surgery, and people with an autoimmune condition known as pernicious anemia

2009 May 15;24(7):979-83