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PubMed Central, Wang, Lu, et al

The classic symptoms of holocarboxylase synthetase deficiency are hypotonia, lethargy, seizures, metabolic acidosis, vomiting, hyperammonemia, developmental delay, skin rash, and alopecia

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Table 1 A summary compiling key studies and reviews that have described limb-related sensory symptomssuch as tingling, cramping, twisting, coldness, or sensory lossin the context of hyperglycemia or diabetic neuropathy

We do not recommend self-administering or seeking frequent IV therapy without proper medical guidance, as this can pose unnecessary health risks

What you need to do is find out what is going on with your body and how it works