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The levels of these mediators usually exhibit modest correlations, thereby limiting the assignment of molecular meaning and the understanding of global relationships [25]
The synergistic action of cell wall proteins (such as Hwp1, Als3) and mannan can mediate the adhesion of fungi to host epithelial cells and extracellular matrix (Mayer et al., 2013), while the dynamic remodeling of -glucan and chitin supports hyphal extension and tissue penetration (Staniszewska, 2020)
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Cell Cycle 12 , 278288 (2013)
showed that intracellular glutamate accumulation following cyst(e)ine depletion or system x C - inhibition is a key contributor to the induction of ferroptosis, and glutamate toxicity can be alleviated by converting excess glutamate to -glutamyl-di- or tripeptides via promiscuous enzymatic activities of glutamate-cysteine ligase catalytic subunit (GCLC) 12
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