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In the STEP-HFpEF trial (Effect of Semaglutide 2.4 mg Once-Weekly on Function and Symptoms in Subjects With Obesity-Related Heart Failure With Preserved Ejection Fraction), the GLP-1 analog semaglutide improved exercise function, HF-related symptoms, and NT-proBNP (N-terminal pro-B-type natriuretic peptide) levels in patients with HFpEF and obesity without diabetes
Heres what you should know to choose between your options: Sildenafil Sildenafil (generic Viagra) is a phosphodiesterase 5 (PDE5) inhibitor
It is available through compounding pharmacies in the United States under physician supervision
[Accessed 1 Mar 2024] Eli Lilly and Company 2021
it is a critical factor in patient compliance and therapeutic efficacy
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