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Why Detoxification Matters: The liver is the primary organ responsible for detoxifying the body, and glutathione is essential for supporting liver function

Expect a series, not a single shot

Moving forward, the most realistic near-term translational path lies in combining relatively simple, biocompatible bone-targeted nanocarriers (such as alendronate-functionalized liposomal or polymeric systems) to specifically co-deliver immunogenic cell death (ICD)-inducing standard chemotherapeutics alongside established immune checkpoint inhibitors (e.g., anti-PD-1/PD-L1) or myeloid cell modulators

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HR 0.69, 95% CI 0.560.84

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