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In some of the cases occasional scattered necrotic fibers were observed (Table 2)

Common side effects include nausea, vomiting, diarrhoea, constipation, abdominal discomfort, bloating, headache and fatigue

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Consequently, on top of the beneficial effect of weight loss caused by GLP-1 analogues these drugs also cause a substantial reduction of the glycemic load (GL = carbohydrate intake X Glycemic index), which per se reduces hyperinsulinemia and causes weight loss [22], reduce diabetes risk [23], inflammation [24], and cardiovascular risk [25]

Aleksic T, Gray N, Wu X, Rieunier G, Osher E, Mills J, et al