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However, chronic injury impairs the synthesis of glycocalyx components and alters their structure, making the glycocalyx more susceptible to external stressors [128]

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160 mg p=0.003) and dose-dependent increase of GLP-1 versus placebo control was detectable, even in the small patient population in this phase 1b clinical trial (baseline: N placebo = 11, N 80 mg IMU-856 = 13, N 160 mg IMU-856 = 13)

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