switching from wegovy to tirzepatide TrimRX Switching from Wegovy to Mounjaro:

[54] in women with PCOS, BMI 25 kg/m 2 and/or insulin resistance, treatment with liraglutide 1.8 mg/day for 26 weeks, along with a higher weight loss, induced significant reductions in fasting plasma glucose, HbA1c, and plasma glucose AUC, whereas Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), Matsuda index and insulin AUC remained unchanged

Tirzepatide may be appropriate for some patients seeking greater average weight-loss outcomes, while Ozempic may be a suitable option for others based on their medical history, treatment goals, insurance coverage, and clinician's recommendation

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The result "makes perfect biological sense," says Adam Auton, study co-author and vice president of human genetics at the 23andMe Research Institute