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Concurrent deficiencies in vitamin D, likely due to reduced sunlight exposure, and fluctuations in estradiol, progesterone, and DHEAS, especially among premenopausal women and extreme chronotypes, further exacerbate endocrine disruption 272

Science Mechanism of Action Epithalon's proposed anti-aging effects work through several connected pathways

Understanding this cycle helps explain why maintaining high levels of the "reduced" form is so important for daily wellness

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Others consider saline options like sodium chloride for specific applications

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