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Thus, oxidative stress, which is the result of an imbalance between prooxidants and antioxidants towards the former due to excessive production of free radicals and/or a decrease in the activity of antioxidant defense, underlies the pathogenesis of many diseases and its study in modeling experimental pathology serves as a fundamental basis for clinical research

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In our previous study, pegylated arginase I treatment may reduce OTC protein expression in human T-ALL cell lines and also hMSCs [153]

Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits

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