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They found that piperazine erastin significantly decreased the size and number of tumor foci in the liver of DEN/CCl4-induced mice and the volume of Bel-7402 cell xenografts, accompanied by reduced levels of GPX4 expression

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10.3389/fimmu.2019.02090 234 QiX.AiyasamyK.AleneziS

Acknowledgements The authors acknowledge assistance from the Principal, Vice Principal, and Management of Calcutta Institute of Pharmaceutical Technology & Allied Health Sciences, West Bengal, India, and from the Director, School of Pharmacy, Techno India University, West Bengal, India for imparting help and support in completion of this review

It has gained attention for its anti-aging, telomere-protecting, and hormone-regulating effects