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An unexpected finding in our studies was the loss of improved lipid tolerance in Dpp4 EC/ mice, with or without coadministration of sitagliptin, following BMT, implying an interaction between bone marrowderived cells and the metabolic actions emanating from the reduction of DPP-4 activity in endothelial cells
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The proportional hazards assumption found no significant interaction in follow-up time and use of a GLP1 ( P = .82)
Useful discussion topics include allergies, active skin disease, medications, pregnancy or breastfeeding, diabetes, abnormal wound healing, infection risk, immune status, and whether approved alternatives are available [7], [8], [11]
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