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The International Journal of Biochemistry & Cell Biology, 37 (8), 1727-37

Contraindications against participating in melanotan research include a medical and family history of melanoma or other skin cancers, known allergies to melanotan, and severe hepatic and renal diseases

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It can improve symptoms of PCOS by helping with weight loss and insulin sensitivity

There is also a credentialing transparency issue here

A compounding industry leader estimates that about 10 million Americans take compounded versions of the drugs, at least twice the number who take name brands