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The paper remains the most-cited single source for GHK-Cus pleiotropic gene-expression effects and is a primary reference for the compounds research applications in dermal aging, wound healing, and oxidative stress models
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K., Goh, C
The significant changes in antioxidant enzyme activity after GSH depletion suggest that thiol status can influence the regulation of other antioxidant enzymes
GHK-Cu is one of the few peptides to benefit from a rigorous scientific corpus simultaneously covering molecular biology (activation of more than 4000 genes in cutaneous fibroblasts, Pickart 2015 BioMed Research International), clinical dermato-regeneration (healing, anti-ageing, damaged skin) and hair aesthetics (documented trichological protocols)
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