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Next, 400 l of concentrated blood was pipetted into a small tube, sealed and frozen at 80C
Parkinsons disease Parkinsons disease (PD) is a long-term neurodegenerative disorder that affects the motor system, characterized primarily by the death of dopaminergic neurons in the substantia nigra and the presence of intracellular aggregates of misfolded -synucleine (Lewy bodies) in the surviving neurons 54,55
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Moreover, MQC collapse impairs autophagosome-lysosome fusion, causing immature autophagosome accumulation and aggravating ACD
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