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Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity
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In the SELECT trial, semaglutide reduced high-sensitivity C-reactive protein (an inflammatory marker) by 37.8%a reduction large enough to move patients from high cardiovascular risk (greater than 3 mg/dL) to intermediate risk (1-3 mg/dL)
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Other data also links GLP-1 use to lower dementia risk in diabetics compared to sulfonylureas or insulin
Chaput, Jean-Philippe, PhD and Angelo Tremblay, PhD
If semaglutide is part of your care plan or youre considering it, speak openly with your pharmacist or prescriber about your health goals, budget, and insurance coverage
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