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If emesis occurs, reduce the rate by 50%

This is a big shoe to drop from a validation standpoint

Courts have reasoned that challenging substantiation is best left for state agencies and the Federal Trade Commission, so private individuals must actually allege the existence of extrinsic evidence, such as conflicting studies, that would show that the challenged statement is false or misleading

If you're experiencing significant head pain, pausing dose escalation for one additional week allows your nervous system to adapt before moving to the next tier

Fischer et al., 2003)