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Semaglutide, an FDA-approved once-weekly injection, has been proven to help people lose weight and maintain it

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What we see is that the efficacy, safety, and tolerability are really consistent with the very best injectable GLP-1s, says Kenneth Custer, president of cariometabolic health at Eli Lilly, of the companys experimental pill

When nausea, vomiting, or diarrhea occur as side effects of GLP-1 medications, dehydration can leave you feeling even more fatigued

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That said, interest alone is not enough to determine whether microdosing is appropriate