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GSH is at 110 mM concentrations in all mammalian tissues (highest concentration in liver) as the most abundant non-protein thiol that protects against excessive oxidative stress

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Betaine's special thing is being an osmolyte , a molecule that helps to control cell-water balance

The reference standard is scintigraphy : a test meal is labeled with a radioisotope, and a gamma camera tracks how quickly the labeled contents leave the stomach, yielding a half-emptying time (the T values quoted earlier for pramlintide came from this class of method)

At 3.0 mL, the higher doses exceed the syringe capacity and require either a different syringe type or splitting the dose into two injections

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