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Los efectos secundarios de tirzepatida son una consideracin importante para pacientes que inician este medicamento inyectable aprobado para diabetes tipo 2 y manejo del peso
Phase 3 outcomes (2026): TRIUMPH-1 (May 2026, n=2,339) demonstrated 28.3% mean weight loss at 12mg weekly the largest published Phase 3 result of any GLP-1 class compound to date, exceeding tirzepatide (22.5% in SURMOUNT-1) and semaglutide (14.9% in STEP-1) at comparable timepoints
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Holotranscobalamin (active B12) where available, this is a more sensitive early marker of B12 depletion and may be preferred in some settings [12] [15] Full blood count to identify macrocytosis or anaemia Folate levels as folate deficiency can co-exist and confound the clinical picture Methylmalonic acid (MMA) and homocysteine functional markers of B12 status, useful when serum B12 is borderline
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