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This means it activates both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), hormones that naturally regulate your appetite and blood sugar

Lyophilized semaglutide can tolerate room temperature for 3-4 weeks, making it more forgiving than many peptides

Br Med Bull 136:118126

In large-scale studies, semaglutide (the active ingredient in Ozempic and Wegovy) led to an average placebo-corrected weight loss of about 12.4% at the 2.4 mg dose

Therefore, the purpose of this scoping review is to characterize the current evidence base for peptide therapies relevant to musculoskeletal care, with emphasis on BPC-157, thymosin beta-4 derivatives, and related agents, and to define safety considerations and perioperative implications for orthopaedic surgical patients, including those undergoing TJA