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DPP-4 inhibitors can on the other hand also be combined with an oral therapy with a SGLT-2 inhibitor (in dual combination when metformin is contraindicated or not tolerated or in triple therapy with metformin)
8 (download XLSX Fibre photometry-mediated calcium traces for each individual mouse
J Pharmaco
The Aib residue at position 2 and the fatty acid modification both confer resistance to the primary degradation enzymes (DPP-4 and neprilysin), extending the metabolic half-life
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Research themes include pigmentation, neuronal repair, neuroendocrine signaling, and behavioral modulation
Glucose-dependent insulinotropic polypeptide augments glucagon responses to hypoglycemia in type 1 diabetes
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