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In contrast, Ultomiris failed to significantly improve event-free survival over placebo in adults and adolescents with HSCT-TMA, marking the latest setback for AstraZeneca's pipeline after a failed heart disease trial earlier this month and an FDA advisory committee voted against approving its breast cancer therapy in May
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The plate was then washed, followed by the addition of anti-human IgG Fc conjugated to HRP (Invitrogen) and incubation for 2 h at room temperature
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