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This constant degranulation generates even more free radicals, which in turn causes more oxidative stress, further depleting the remaining glutathione

For patients with type 2 diabetes who maintained a stable weight, GLP-1 use was associated with an 8.7% lower osteoporosis risk compared to patients who did not use a GLP-1, as seen in Figure 1

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Furthermore, the extent of mucosal injury correlates with the depletion of mucosal GSH whereas mucosal GSH recovery by GSH ester administration preserve intestinal integrity (Martensson et al, 1990)

Researchers compared patients taking GLP-1 drugs with those using other diabetes medications

Manage Stress: High stress increases the production of free radicals, which can quickly drain your antioxidant stores